Rules, as amended from time to time, are liable to be set aside as being repugnant to the Pharmacy Act, 1948 and the Pharmacy Practice Regulations, 2015 framed thereunder by the Pharmacy Council of India. It was submitted that the Pharmacy Act, 1948 is a Central legislation occupying the field relating to regulation of the profession of pharmacy, including qualifications, registration, professional responsibilities and ethical standards of Pharmacists. The Regulations framed by the PCI in exercise of statutory powers under Sections 10 and 18 of the Act, it was urged, have statutory force and prevail over Rules framed by the State under the proviso to Article 309 of the Constitution of India. The Regulations prescribe the qualification for the post of Pharmacist as Diploma in Pharmacy or Bachelor in Pharmacy. In terms of these Regulations, both categories of candidates are eligible to be appointed as Pharmacists. Fixation of Diploma in Pharmacy as the sole basic qualification under the State Rules runs directly contrary to the Regulations. Further, the Pharmacy Council of India vide letter dated 07.10.2022 clarified that the Regulations framed by the PCI are binding on the State Governments to implement the same with immediate effect. Thus, to the extent the Cadre Rules prescribe eligibility criteria inconsistent with the central enactment and the Regulations, they were asserted to be ultra vires.